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Metabolic

MOTS-c

99.3% HPLC Verified Purity
CAS Number1627580-64-6
Molecular Weight2174.59 g/mol
Molecular FormulaC100H152N28O22S2
Storage-20 °C, lyophilized
$50.00/ vial
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RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
MOTS-c

What is MOTS-c?

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a synthetic 16-amino acid peptide encoded in the mitochondrial genome. With the molecular formula C₁₀₁H₁₅₂N₂₈O₂₂S₂ and a molecular weight of 2174.6 g/mol (CAS: 1627580-64-6), MOTS-c represents a unique mitochondrial-derived peptide with metabolic regulatory functions.

Amino Acid Sequence:MRWQEMGYIFYPRKLR
Classification: Mitochondrial-Derived Peptide (MDP)FGF21 PathwayAMPK Signaling

Specifications

CAS Number1627580-64-6
Molecular FormulaC100H152N28O22S2
Molecular Weight2174.59 g/mol
Purity≥99.3% (HPLC verified)
FormLyophilized powder
Storage-20 °C, lyophilized
ShippingInsulated protective packaging

Mechanism of Action

AMPK Pathway

AMP-activated protein kinase

MOTS-c activates AMPK signaling, influencing cellular energy metabolism in muscle and fat cell models.

FGF21 Expression

Fibroblast growth factor 21

Research indicates MOTS-c increases FGF21 expression, affecting metabolic gene networks in adipose tissue cultures.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Mitochondrial-derived peptide with unique origin and metabolic functions.

Related Compounds

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Scientific Context

Related Research & Analysis

Metabolic

Comparative Pharmacodynamics of Metabolic Peptides: GLP-1, GIP, and Dual Agonist Research

A research-focused comparison of GLP-1, GIP, and dual GIP/GLP-1 agonist peptides including tirzepatide, examining receptor binding, metabolic mechanisms, and published research outcomes.

Read Full Article