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Cognitive

Semax

99.5% HPLC Verified Purity
CAS Number80714-61-0
Molecular Weight813.93 g/mol
Molecular FormulaC37H51N9O10S
Storage-20 °C, lyophilized
$30.00/ vial
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RESEARCH USE ONLY: This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Not evaluated by the FDA. Must be 21+ to purchase.
Semax

What is Semax?

Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4-10 with modifications. With the molecular formula C₃₇H₅₁N₉O₁₀ and a molecular weight of 812.9 g/mol (CAS: 80714-61-0), Semax consists of the sequence Met-Glu-His-Phe-Pro-Gly-Pro with an N-terminal proline and C-terminal glycine-proline added.

Amino Acid Sequence:Pro-Gly-Pro-Glu-His-Phe-Met
Classification: ACTH Fragment AnalogBDNF/TrkB PathwayNeurotrophic Factors

Specifications

CAS Number80714-61-0
Molecular FormulaC37H51N9O10S
Molecular Weight813.93 g/mol
Purity≥99.5% (HPLC verified)
FormLyophilized powder
Storage-20 °C, lyophilized
ShippingInsulated protective packaging

Mechanism of Action

BDNF/TrkB Signaling

Neurotrophin receptor activation

Semax increases brain-derived neurotrophic factor expression and activates TrkB receptors in neuronal cultures.

Gene Expression

Transcriptional regulation

Research demonstrates Semax modulates expression of genes involved in neuroplasticity and neurotrophic factor production.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Derived from ACTH fragment 4-10 with neuroprotective modifications.

Related Compounds

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Scientific Context

Related Research & Analysis

Cognitive

Neuroactive Peptide Profiles in Cognitive Research: Comparative Mechanisms of Semax, Selank, and Dihexa

Research-focused comparison of Semax, Selank, and Dihexa examining BDNF modulation, anxiolytic mechanisms, HGF/c-Met signaling, and neuroprotective findings in published literature.

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